Orthopedic injury or disease affects millions of Americans


Osteoarthritis is one such a degenerative disease that can be a crippling source of joint pain.

Most commonly found in knees and hips, this disease leads to significant disability and loss of function, as well as other co-morbidities. Typical treatment options for these orthopedic areas include physical therapy, injection of steroids or cartilage substitutes, or joint replacement. These options can provide temporary relief, however they may damage local tissues and require extensive recovery or rehab.

Osteoarthritis or painful knee joint is a serious and widespread problem. Roughly half of all adults will have issues with osteoarthritis during their life. It is responsible for limiting people’s movements and enjoyment of life. When people can’t perform their usual activities, they have a much lower satisfaction of life and are at risk for developing Sarcopenia, or weak muscles and putting on excessive weight. Being less active and adding weight puts one at risk for developing adult onset diabetes and cardiovascular disease. So, a common problem can unknowingly spiral into a life-threatening illness.

The pain limits their interactions with family and the ability to do things they enjoy such as walking, shopping or spending time with friends. In many instances, the pain at night is severe enough to keep people awake which causes sleepiness and fatigue during the day. Osteoarthritis is the biggest factor that causes functional impairment on a daily basis for adults and has a huge negative impact on the quality of life.

Many factors predispose to osteoarthritis such as the history of previous trauma like a torn ligament or cartilage or having an active life style. Caucasians and women are at higher risk for developing osteoarthritis.

Standard medical treatments do not provide adequate relief for this common debilitating problem. Usual treatments for osteoarthritis include muscle strengthening exercises, weight management, and topical nonsteroidal anti-inflammatory medications, knee brace or walking cane and finally total knee replacement.

There are many studies that show a benefit from stem cell therapy in osteoarthritis. Many are listed on the website.  These studies in summary, indicate that a higher number of stem cells and a longer time after injection are necessary to have optimal improvement.

At Pittsburgh Stem Cell we are a member of the Cell Surgical Network which has over 50 centers worldwide. The stem cell treatments that we offer are part of an investigational study, so we are closely tracking our results to provide information on the outcomes of treatments. The Department of Health and Human Services has appointed an Institutional Review Board (IRB) which monitors these studies for patient safety. Since these studies are investigational, insurance coverage for payment is not an option.

The Cell Surgical Network has published 8 articles on stem cell therapy and expects another publication later in 2019.


Regenerative Medicine Approach:

A healthy diet eliminating inflammatory foods

Attaining optimal body weight

Muscle strengthening under the professional guidance of a Doctor of Chiropractic or Doctor of Physical Therapy.

Bio-identical hormone balance to assist with strength and muscle healing

Peptide Therapy to optimize Growth Hormone level and Growth Factors which may stimulate your own stem cells to grow and heal

Anti-Inflammatory supplements to calm the hostile environment in the knee joint

Biological therapy such as Stem Cell, PRP or in the future Exosomes

At your consultation, Doctor Wharton will review your medical history and develop a plan that will address the goals that you would like to attain.


There is minimal risk associated with Autologous stem-cell therapy, and there is great potential for increased healing.

Learn more about what is involved in a typical stem-cell therapy appointment.